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                                                        Highlights

                                                        Open Access Nature Cardiocascular Research https://www.nature.com/articles/s44161-023-00413-9

                                                        New signalling pathway uncovered, shedding fresh light on atherosclerosis

                                                        NATURE CARDIOVASCULAR RESEARCH 2024 ➤ IPEK scientists from the Weber and Döring Labs have found new mechanisms involved in the development of inflammatory cardiovascular diseases.

                                                        Weber Lab | IPEK

                                                        Atherosclerosis: RNA fragment creates prospect for new therapies

                                                        SCIENCE TRANSLATIONAL MEDICINE 2023  ➤ IPEK researchers have demonstrated for the first time what role a specific microRNA plays in atherosclerosis – and how it manages to intervene in this signaling…

                                                        T cells and atherosclerosis: the good, the bad, and the unknown

                                                        NATURE CARDIOVASCULAR RESEARCH 2023  ➤ IPEK scientists describe that atherosclerosis leads to disorders of the immune system, similar to those in known autoimmune diseases. Pairing of single-cell RNA…

                                                        2022
                                                        National Institutes of Allergy and Infectious Diseases, National Institutes of Health

                                                        Atherosclerosis: how the body controls the activity of B cells

                                                        NATURE CARDIOVASCULAR RESEARCH 2022  ➤ IPEK scientists have identified a protein that is involved in the regulation of immune cells and can curb the development of atherosclerosis.

                                                        How antibodies get it wrong

                                                        CELL STEM CELL 2022 ➤  IPEK scientists alert to the wrong use of antibodies in scientific publications. In their recent work, they refute a specific study on localization of immune receptor ACKR1.

                                                        @LMU

                                                        Atherosclerosis: How diseased blood vessels communicate with the brain

                                                        NATURE  2022 ➤ IPEK scientists have been able to demonstrate for the first time that nerve signals are exchanged between arteries and the brain in atherosclerosis.

                                                        Vectormanzone | Vecteezy.com

                                                        Arterial thromboses: innovative treatment approach

                                                        BlOOD 2022 ➤ IPEK scientists have shown in an animal model that the CXCL12 messenger could be suitable as a target structure for the treatment of blood-clotting disorders

                                                        2021
                                                        LMU Klinikum

                                                        BTK inhibitors against vaccine-related thrombotic complications

                                                        NEJM 2021 ➤ IPEK scientists propose treatment for rare, life-threatening complication from Astra-Zeneca vaccine.

                                                        Chuttersnap | Unsplash

                                                        Why is the risk of heart attack higher early in the day

                                                        CIRCULATION 2021 ➤ In the journal Circulation, a team led by IPEK scientists Maliheh Nazari-Jahantigh and Andreas Schober provides an answer.

                                                        Atherosclerosis and the immune system

                                                        NATURE  COMMUNICATIONS 2021 ➤ IPEK scientist have uncovered how signal proteins of the immune system regulate the development of atherosclerosis.

                                                        2020
                                                         Dr. Carlos Silvestre-Roig @IPEK

                                                        Reduce heart attack risk after infections

                                                        CIRCULATION 2020 ➤ After an infection, the risk of a heart attack in cardiovascular risk patients increases up to twenty times. IPEK scientists have found that the immune cells are involved in this…

                                                        How a miRNA binds and inhibits Caspase-3 to confer vascular integrity

                                                        SCIENCE TRANSLATIONAL MEDICINE 2020  ➤ IPEK scientists have discovered a hitherto unknown molecular function of a specific microRNA that preserves integrity of the endothelium and reduces the risk of…

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